World Arthritis Day ndi mwambo wodziwitsa anthu za umoyo wapadziko lonse lapansi womwe umachitika chaka chilichonse pa 12 Okutobala kuti udziwitse anthu za matenda a nyamakazi ndi minofu ndi mafupa, momwe amakhudzira moyo wamunthu komanso kuphunzitsa anthu zazizindikiro ndi njira zodzitetezera ndikuwongolera matenda am'mbuyomu kuti athe kuthana ndi zovuta zina. .
Kufunika kwa Tsiku la Arthritis Padziko Lonse (WAD)
Matenda a nyamakazi ndi matenda otupa olowa m'malo olumikizirana mafupa, omwe amakhudza minofu yozungulira yolumikizana, ndi ziwalo zina zolumikizirana, zomwe zimayambitsa kupweteka komanso kuuma kwa mafupa.Mitundu yoposa 100 ya nyamakazi ilipo, koma yofala kwambiri ndi nyamakazi ndi nyamakazi.Chifukwa cha kusowa kwa chidziwitso ndi chithandizo, nyamakazi ndi momwe zimayenderana nazo zalepheretsa moyo wambiri padziko lonse lapansi.Palibe mankhwala enieni a nyamakazi, njira yochizira imasiyanasiyana malinga ndi mitundu yake, chifukwa chake ndikofunikira kumvetsetsa chizindikiro ndi zizindikiro ndikuzindikira msanga kuti mupeze chithandizo choyenera.
Matenda Odziwika Kwambiri a Nyamakazi
Mitundu yodziwika kwambiri ndi nyamakazi ya osteoarthritis (OA), nyamakazi ya nyamakazi (RA), nyamakazi ya psoriatic (PsA), fibromyalgia ndi gout.Matenda a nyamakazi ndi matenda okhudzana nawo angayambitse kupweteka, kusintha moyo m'njira zosiyanasiyana.
Matenda a nyamakazi (RA) ndi amodzi mwa matenda otupa olowa m'malo ambiri, omwe amapezeka mwa amayi azaka zapakati.Makamaka kuwonetseredwa monga aakulu, symmetrical, patsogolo polyarthritis.Kuphatikiza pa kukhudza mafupa, pali mawonetseredwe ambiri owonjezera, monga khungu, maso, mtima, mapapo, magazi, ndi zina zotero.
Kuchuluka kwa RA ndi 0.5-1%, ndi chiŵerengero cha mkazi ndi mwamuna cha 3: 1.Kuchulukitsa kuwirikiza ka 4 mpaka 5 mwa akazi osakwana zaka 50, koma pakatha zaka 60 chiŵerengerocho chimakhala pafupifupi 2 mpaka 1.Anthu omwe ali ndi nyamakazi ya nyamakazi nthawi zambiri amakhala ndi mlingo wapamwamba wa C-reactive protein (CRP), womwe ukhoza kusonyeza kukhalapo kwa njira yotupa m'thupi.Kuyeza kwina kwa magazi komwe kumachitika kawirikawiri kumayang'ana ma antibodies a rheumatoid factor (RF) ndi anti-cyclic citrullinated peptide (anti-CCP).
RA(Matenda a nyamakazi)
Rheumatoid nyamakazi ndi matenda otupa omwe amatha kukhudza zambiri kuposa mafupa anu.Kwa anthu ena, matendawa amatha kuwononga machitidwe osiyanasiyana a thupi, kuphatikizapo khungu, maso, mapapo, mtima ndi mitsempha ya magazi.
Matenda a autoimmune, nyamakazi ya nyamakazi imachitika pamene chitetezo chanu cha mthupi chimaukira molakwika minofu ya thupi lanu.
Mosiyana ndi kuwonongeka kowonongeka kwa osteoarthritis, nyamakazi ya nyamakazi imakhudza chingwe cha mafupa anu, kuchititsa kutupa kowawa komwe kungayambitse kukokoloka kwa mafupa ndi kupunduka kwa mafupa.
Anti-CCP Anti-Cyclic Citrullinated Peptide Antibody
Anti-cyclic citrullinated peptide antibody (Anti-CCP): Ndi polypeptide fragment ya cyclic polyguanidine protein ndipo makamaka IgG-type antibody.Anti-cyclic citrullinated peptide antibodies amatulutsidwa ndi B lymphocytes odwala nyamakazi (RA), pamene B lymphocytes odwala matenda ena ndi anthu wamba samangotulutsa anti-cyclic citrullinated peptide antibodies.Chifukwa chake, ili ndi chidwi chachikulu komanso chodziwika bwino cha nyamakazi ya nyamakazi, ndipo ndi chizindikiro chodziwika bwino cha matenda a nyamakazi ya nyamakazi.
Anti-CCP (Anti-cyclic citrullinated peptides) ndi mtundu wa anti-antibody: antibody yomwe imagwira ntchito motsutsana ndi ma antibodies abwinobwino a thupi lanu.Anti-CCP imapangidwa nthawi zambiri mukakhala ndi nyamakazi.Ma autoantibodies awa amayamba kulunjika ndikuukira minofu ina yathanzi.
Zizindikiro zoyamba za nyamakazi ya nyamakazi: ma anti-cyclic citrullinated antibodies amawonekera zaka 1-10 zisanachitike mawonetseredwe a matenda a nyamakazi, oyenera kuyang'anira anthu athanzi komanso kuzindikira koyambirira kwamagulu omwe ali pachiwopsezo chachikulu.Pakadali pano,akukhulupirira kuti tilinazo odana cyclic citrullinated peptide oteteza kuti matenda a nyamakazi nyamakazi ndi 50% mpaka 78%, yeniyeni ndi 96%, ndi mlingo wabwino odwala oyambirira akhoza kufika 80%.
AehealthAnti-CCP Pnjira
Aehealth Anti-CCP (Anti-cyclic Citrullinated Peptide Antibody) Rapid Quantitative Test amatengera njira ya Immunofluorescence Assay.
Kuzindikira kwa zida za Anti-CCP ndi 10 ~ 500 U/mL;mizere yolumikizirana pakati pa ndende yamalingaliro ndi ndende yoyezera imatha kufika pa r≥0.990.Amagwiritsidwa ntchito ndi Aehealth Lamuno X immunofluorescence kusanthula kuperekeza kuzindikira koyambirira komanso kuwunika kwamankhwala kwa odwala rheumatism.
Ma antibodies anti-CCP amalumikizana ndi magawo a zochita za RA.
Ma antibodies anti-CCP amaneneratu kuwonongeka kwa RA.
Nthawi yotumiza: Oct-12-2022