Makhalidwe Antchito
Kuzindikira malire: 0.08ng/mL;
Mzere wa Linear: 0.08 ~ 10.00 ng / mL;
Linear coefficient R ≥0.990;
Kulondola: mkati mwa batch CV ndi ≤15%;pakati pa magulu CV ndi ≤20%;
Kulondola: kupatuka kwapang'onopang'ono kwa zotsatira zoyezera sikudutsa ± 15% pomwe choyezera cholondola chokhazikika chikuyesedwa.
1. Sungani chojambulira nkhokwe pa 2～30℃.Buffer imakhala yokhazikika mpaka miyezi 18.
2. Sungani kaseti yoyesera ya Aehealth Ferritin Rapid Quantitative pa 2～30℃, alumali amakhala mpaka miyezi 18.
3. Kaseti yoyesera iyenera kugwiritsidwa ntchito pasanathe ola limodzi mutatsegula paketi.
Mapuloteni a S100 anapezeka mu ubongo wa ng'ombe ndi Moore BW mu 1965. Amatchulidwa kuti mapuloteni amatha kusungunuka mu 100% ammonium sulfate.Magawo awiri α ndi β amaphatikizana kupanga S100αα, S100αβ, ndi S100-ββ.Pakati pawo, mapuloteni a S100-β (S100αβ ndi S100-ββ) amatchedwanso mapuloteni apakati a mitsempha, ndipo akatswiri ena amafotokoza kuti ndi "C-reactive protein" ya ubongo.Mapuloteni omanga kashiamu wa asidi okhala ndi molekyu yolemera 21KD amapangidwa makamaka ndi astrocyte., Kupyolera mu mapangidwe a disulfide zomangira ndi zotsalira za cysteine, zimakhalapo mkatikati mwa mitsempha yambiri mu mawonekedwe a ntchito ya dimer.
Mapuloteni a S100-β ali ndi zochitika zambiri zamoyo ndipo amagwira ntchito yofunika kwambiri pakukula kwa maselo, kusiyanitsa, kufotokozera kwa majini, ndi apoptosis ya maselo.Pansi pa zochitika za thupi, mapuloteni a S100-β mu ubongo amasonyezedwa mofooka pa tsiku la 14 la embryonic stage, ndiyeno amawonjezeka mofanana ndi kukula ndi chitukuko cha mitsempha ya mitsempha, ndipo imakhala yokhazikika pauchikulire.Mapuloteni a S100-β ndi neurotrophic factor mu chikhalidwe cha thupi, chomwe chimakhudza kukula, kufalikira ndi kusiyanitsa kwa maselo a glial, kusunga calcium homeostasis, ndipo imagwira ntchito inayake pakuphunzira ndi kukumbukira, ndikulimbikitsa kukula kwa ubongo;pamene anthu ali ndi matenda a maganizo Matenda, kuvulala kwa ubongo (cerebral infarction, kuvulala kwa ubongo, kuvulala kwa ubongo pambuyo pa opaleshoni ya mtima, ndi zina zotero) kapena kuvulala kwa mitsempha, mapuloteni a S100-β amachokera ku cytosol kupita ku cerebrospinal fluid, ndiyeno amalowa m'magazi kudzera mu zowonongeka. Chotchinga chamagazi ndi ubongo, potero Izi zimabweretsa kuchuluka kwa mapuloteni a S100-β m'magazi.
Monga chizindikiro cha biochemical cha kuvulala kwa ubongo, S100-βmapuloteni amakhala ndi nthawi yosintha pambuyo povulala muubongo, ndipo amagwirizana kwambiri ndi kuchuluka kwa kuvulala kwaubongo ndi momwe amanenera, ndipo amakhala okhazikika.Kuzindikira kwa mtengo wake wokhazikika kumathandiza pakuwunika kwachipatala kwa mitsempha.Kukula kwa chotupa cha minofu, chithandizo chamankhwala komanso momwe munthu amakhalira.